Características audiológicas y tratamiento con hormona de crecimiento en niñas con síndrome de Turner: estudio retrospectivo en un hospital pediátrico de referencia

Mary Eugenia Posada Alvarez; Carlos  De La Torre González

doi:10.37076/acorl.v54i3.923

PDF (Spanish)

Published: 2026-09-16

DOI: https://doi.org/10.37076/acorl.v54i3.923

Keywords:

syndrome turner, Otolaryngology, Pediatrics, Hearing, Growth Hormone

Mary Eugenia Posada Alvarez

Otorrinolaringóloga pediatra y rinóloga. Alta especialidad en cirugía endoscópica sinonasal avanzada y base de cráneo, epidemióloga clínica. Hospital Serena del Mar, Cartagena, Colombia

https://orcid.org/0000-0003-0935-6188

Carlos De La Torre González

Otorrinolaringólogo pediatra, jefe del Servicio de Otorrinolaringología del Hospital Infantil de México, “Federico Gómez”. Profesor titular de la subespecialidad de Otorrinolaringología Pediátrica, UNAM

https://orcid.org/0000-0002-0196-4130

Abstract

Introduction: Turner syndrome results from the partial or complete absence of one X chromosome and is a condition that affects female patients. Conductive hearing loss has been associated with various conditions such as recurrent otitis media, structural abnormalities of the skull base, and alterations in the SHOX gene.

Objective: To describe the audiological characteristics of pediatric patients with Turner syndrome treated with recombinant growth hormone at the Federico Gómez Children's Hospital of Mexico.

Methods: A case-control study was conducted. Pediatric patients with a cytogenetic diagnosis of Turner syndrome by fluorescence in situ hybridization (FISH) were included. These patients were treated between January 1, 2016, and December 31, 2021, and had audiological evaluations documented in their medical records. All patients were treated with recombinant growth hormone.

Results: Forty-three patients were included, 29 in the Growth Hormone group and 14 in the control group. The median age was 7.17 years for the Growth Hormone group and 8.39 years for the control group. All patients underwent audiological evaluation, and it was found that recombinant growth hormone therapy did not alter the hearing pattern in girls with Turner syndrome.

Conclusion: This study serves as a reference for future research aimed at expanding the description of the specific characteristics of this population, thereby improving patient care and contributing to new knowledge in the field of pediatric otolaryngology.

Issue

Vol. 54 No. 3 (2026): Julio - Septiembre

Section

Trabajos Originales

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eISSN: 2539-0856

ISSN: 0120-8411

How to Cite

1.

Audiological characteristics of pediatric patients with Turner syndrome managed with growth hormone. Acta otorrinolaringol cir cabeza cuello [Internet]. 2026 Sep. 16 [cited 2026 Sep. 16];54(3):239-50. Available from: https://mail.revista.acorl.org.co/index.php/acorl/article/view/923

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