Papillary cancer in thyroglossal duct cyst: A case series

Main Article Content

Javier Isaac Molina Velasquez

Abstract

Introduction: Thyroglossal duct cysts (TGDC) are unusual remnants of the thyroid gland. Papillary carcinoma of the thyroglossal duct is extremely rare in clinical prac­tice. Case series: Four cases of patients with papillary carcinoma of the thyroglossal duct cyst are presented. Discussion: Papillary carcinoma of the thyroglossal duct cyst is considered a rare finding, occurring in approximately 1% of thyroglossal duct cyst cases. Total, thyroidectomy is recommended for cases with malignant trans­formation, especially if there is evidence of invasion or when the tumor exceeds 1 centimeter in size. Conclusion: Carcinomas arising from thyroglossal duct cyst remnants are rare and may present only as swelling of the anterior neck. The need for thyroidectomy due to thyroid disease, whether malignant or benign, is not un­common in patients with thyroglossal duct cyst.

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Reportes de Casos

How to Cite

1.
Papillary cancer in thyroglossal duct cyst: A case series. Acta otorrinolaringol cir cabeza cuello [Internet]. 2026 Feb. 9 [cited 2026 Feb. 10];53(4):359-65. Available from: https://mail.revista.acorl.org.co/index.php/acorl/article/view/826

References

1. Bu F, Yu K, Dong B, et al. Research progress of ectopic thyroid cancer in thyroglossal duct cyst: A case report and literature review. Medicine (Baltimore). 2024;103(26):e38540. doi: 10.1097/MD.0000000000038540.

2. Alrohaimi FA, Alqahtani SM, Almutairi AB. Thyroglossal Duct Cyst Papillary Carcinoma: A Rare Disease Entity. Cureus. 2024;16(10):e70999. doi: 10.7759/cureus.70999.

3. Dai GF, Li SY, Yin YQ, et al. [Thyroglossal Duct Papillary Carcinoma: Report of One Case and Literature Review]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2024;46(5):792-796. Chinese. doi: 10.3881/j.issn.1000-503X.15901.

4. Salih AM, Qaradakhy AJ, Saeed YA, et al. Carcinoma arising from thyroglossal duct remnants. Biomed Rep. 2024;20(4):60. doi: 10.3892/br.2024.1748.

5. Li X, Yang H, Deng X, et al. Thyroglossal Duct Cyst Located in the Thyroid Gland Misdiagnosed With Thyroid Carcinoma: A Case Report and Literature Review. Ear Nose Throat J. 2024;103(2):NP124-NP127. doi: 10.1177/01455613211040583.

6. Shah VS, Vaidya RU, Desai SC, et al. Papillary Carcinoma Within a Thyroglossal Duct Cyst. Cureus. 2024;16(11):e74407. doi: 10.7759/cureus.74407.

7. Podzimek J, Fruth K, Jecker P. High-resolution ultrasound of thyroglossal cysts with special emphasis on the detection of cystic portions above the hyoid within the tongue base. Ultrasound. 2025;33(1):20-26. doi: 10.1177/1742271X241241783.

8. Yanar C, Cetinoglu I, Sengul Z, et al. Coexistence of Thyroglossal Cyst and Thyroid Disease in Adults: Surgical Outcomes From A Single Center. Sisli Etfal Hastan Tip Bul. 2024;58(3):291-297. doi: 10.14744/SEMB.2024.99390.