Surgical Management of Biopolymers in Nasal Tip: Case Report and Literature Review

Main Article Content

Laura Sofia Thomas
Claudia Paola González Saboya
Nicolás Heredia Combariza

Abstract

Injectable facial fillers have been widely used worldwide. There are temporary, semipermanent, and permanent fillers. Regarding permanent fillers silicone is the most widely used, approved by the Food and Drug Administration (FDA) in two presentations Adatosil and Silicon 100 for retinal detachment. In 1997 the FDA allows for the off-label use prescribed within the doctor-patient relationship. There have been reported multiple adverse events, mainly inflammatory symptoms, foreign body reactions, sepsis, and product migration generally occurring by inappropriate application by untrained personnel. Case report: We present the case of a male patient in the fifth decade of life who underwent the application of silicone oil at the level of the nasal tip, and later presented secondary dermatopathy without response to medical management, which requires surgical management to remove the allogeneic material and secondary nasal reconstruction. Discussion: Facial fillers have been widely used, however. 

Article Details

Section

Reportes de Casos

How to Cite

1.
Surgical Management of Biopolymers in Nasal Tip: Case Report and Literature Review . Acta otorrinolaringol cir cabeza cuello [Internet]. 2022 Dec. 30 [cited 2025 Dec. 13];50(4):304-8. Available from: https://mail.revista.acorl.org.co/index.php/acorl/article/view/606

References

1. Chiang YZ, Pierone G, Al-Niaimi F. Dermal fillers: pathophysiology, prevention and treatment of complications. J Eur Acad Dermatol Venereol. 2017;31(3):405-13. doi: 10.1111/jdv.13977

2. Akkary E, Shumway R, Barnett J. Purified Polydimethylsiloxane (Silicone) as Dermal Filler Resolving the Controversy? The American Journal of Cosmetic Surgery. 2019;36(2):71-7. doi:10.1177/0748806818793815

3. Bigatà X, Ribera M, Bielsa I, Ferrándiz C. Adverse granulomatous reaction after cosmetic dermal silicone injection. Dermatol Surg. 2001;27(2):198-200. doi: 10.1046/j.1524-4725.2001.00020.x

4. Hu HC, Fang HW, Chiu YH. Delayed-Onset Edematous Foreign Body Granulomas 40 Years After Augmentation Rhinoplasty by Silicone Implant Combined with Liquid Silicone Injection. Aesthetic Plast Surg. 2017;41(3):637-40. doi: 10.1007/s00266-017-0790-6

5. Alijotas-Reig J, Fernández-Figueras MT, Puig L. Inflammatory, immune-mediated adverse reactions related to soft tissue dermal fillers. Semin Arthritis Rheum. 2013;43(2):241-58. doi: 10.1016/j.semarthrit.2013.02.001

6. Ellis LZ, Cohen JL, High W. Granulomatous reaction to silicone injection. J Clin Aesthet Dermatol. 2012;5(7):44-7.

7. López-Albán CA. Aplicación de biopolímeros o sustancias modelantes como un problema de salud pública en la ciudad de Cali [Internet] [Tesis]. Cali: Universidad del Valle; 2018. Disponible en: https://bibliotecadigital.univalle.edu.co/bitstream/handle/10893/15030/CB-0591793.pdf?sequence=1&isAllowed=y

8. El-Khalawany M, Fawzy S, Saied A, Al Said M, Amer A, Eassa B. Dermal filler complications: a clinicopathologic study with a spectrum of histologic reaction patterns. Ann Diagn Pathol. 2015;19(1):10-5. doi: 10.1016/j.anndiagpath.2014.11.004

9. Rapaport MJ, Vinnik C, Zarem H. Injectable silicone: cause of facial nodules, cellulitis, ulceration, and migration. Aesthetic Plast Surg. 1996;20(3):267-76. doi: 10.1007/s002669900032

10. Mo YW, Lee DL. aaps a decade. 2019;25(3):115–8. 11. Humphrey CD, Arkins JP, Dayan SH. Soft tissue fillers in the nose. Aesthet Surg J. 2009;29(6):477-84. doi: 10.1016/j.asj.2009.09.002

11. Humphrey CD, Arkins JP, Dayan SH. Soft tissue fillers in the nose. Aesthet Surg J. 2009;29(6):477-84. doi: 10.1016/j.asj.2009.09.002

12. Thompson MR, Guerin A, Borba V, Haik J, Harats M, QuirosLim HE, et al. The Downside of Beauty: ASIA Syndrome Associated with Local Silicone injections: A Literature Review. Immunome Res. 2021;16:7391. doi: 10.35248/1745-7580.21.s4.7391

13. Park ME, Curreri AT, Taylor GA, Burris K. Silicone Granulomas, a Growing Problem? J Clin Aesthet Dermatol. 2016;9(5):48-51.

14. Friedmann DP, Kurian A, Fitzpatrick RE. Delayed granulomatous reactions to facial cosmetic injections of polymethylmethacrylate microspheres and liquid injectable silicone: A case series. J Cosmet Laser Ther. 2016;18(3):170-3. doi: 10.3109/14764172.2015.1114642

15. Rho B Il, Yoon SM, Park ES, Wee SY. The Characteristics and Safety of Previous Fillers in Secondary Rhinoplasty. Arch Aesthetic Plast Surg. 2018;24(2):49-54. doi: 10.14730/aaps.2018.24.2.49

Most read articles by the same author(s)